Photo by Jesus Serra-perez

Luxury Hotels in Santa Cruz

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Check prices for these dates

Tonight
Mar 10 - Mar 11
Tomorrow
Mar 11 - Mar 12
This weekend
Mar 14 - Mar 16
Next weekend
Mar 21 - Mar 23

Luxury Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
2 outdoor pools

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (312)
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Cruz

Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.

See properties in Plaza 24 de Septiembre
Plaza 24 de Septiembre

Frequently asked questions

What are the best luxury hotels in Santa Cruz?
One of the top Santa Cruz luxury hotels based on guest reviews is Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Make the most of concierge services and complimentary breakfast during your stay here. Alternatively, step into a world of elegance and comfort at Camino Real Hotel, another traveler favorite in this city.
What are the cheapest luxury hotels in Santa Cruz?
Experience high-end comfort without breaking the bank when you stay in an affordable luxury hotel in Santa Cruz on your next trip. If you’re on a budget, try our “Price: low to high” filter to look for upscale accommodations to suit your price range. Keep a lookout for discounts to help make your getaway even more affordable. You can also sign up for One Key™, our rewards program, to earn discounts on future trips.
What is the best time to stay in a luxury hotel in Santa Cruz?
September is the warmest month, with temperatures ranging from 68ºF (20ºC) to 90ºF (32ºC). If you like cooler weather, organize your trip for June. It’s typically between 61ºF (16ºC) and 75ºF (24ºC) then. February is a good month to experience a more relaxed vibe and potentially lock in more affordable luxury hotels in Santa Cruz.
What luxury hotels in Santa Cruz have a pool?
Begin your day with a swim and end it wrapped in comfort at Camino Real Hotel. Along with a pool, you’ll have access to beauty services and a steam room. Buganvillas Hotel Suites & Spa is another property where lounging by the water is on the itinerary. These Santa Cruz luxury hotels with a pool are where fun and impeccable service come together for the ultimate getaway.
What are the best 5-star luxury hotels in Santa Cruz?
From exceptional service to flawless attention to detail, expect the best of everything at Radisson Hotel Santa Cruz. This 5-star luxury Santa Cruz hotel has everything you need, including golf lessons with a pro and a swimming pool.
Are there any luxury hotels in Santa Cruz with parking?
There are 229 Santa Cruz luxury hotels with parking to choose from. Pull in and kick back in style at Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Every detail is designed to elevate your stay, including concierge services and a garden. Camino Real Hotel is another stay where you’ll find a place to park, along with numerous thoughtful touches.